Abstract Background Proteinuria is an independent risk factor for morbidity and mortality in dogs.An association between proteinuria and gallbladder mucocele formation in dogs is unknown.Objective Determine if gallbladder mucocele formation or clinicopathologic comorbidities are associated with proteinuria.Animals Twenty?five dogs with mucocele for
Characterisation and antibiotic resistance of Yersinia enterocolitica from various meat categories, South Africa
Yersinia enterocolitica infections impose a significant public health and socioeconomic burden on human population in many countries.The current study investigated the prevalence, antimicrobial resistance profile and molecular diversity of Y.enterocolitica in meat and meat products across various retail outlets in selected provinces of South Africa
Early infantile form of galactosialidosis in a female baby with a prenatal diagnosis of fetal ascites: First case in Brazil
We present the first case of Buoyancy Aids an early infantile form of galactosialidosis among Brazilians.This very rare and severe lysosomal storage disease has only a dozen patients clearly diagnosed worldwide.Clinical, pathological and biochemical features were consistent with previously published findings.We detected the disorder in a 7-month-ol
Cytoplasmic ATR Activation Promotes Vaccinia Virus Genome Replication
Summary: In contrast to most DNA viruses, poxviruses replicate their genomes in the cytoplasm without host involvement.We find that vaccinia virus induces cytoplasmic activation of ATR early during infection, before genome uncoating, which is unexpected because ATR plays a fundamental nuclear role in maintaining host genome integrity.ATR, RPA, INTS